[an error occurred while processing this directive]

Paroxetine HCL 78246-49-8

Item Code:78246-49-8 Features:EP
  • Description
Paroxetine Hydrochloride
Chemical name : paroxetine hydrochloride, (-)trans-3-[(1,3-benzodioxol-5-yloxy) methyl]-4-(4-fluorophenyl) piperidine hydrochloride
C A S : 78246-49-8
Structural formula:

Discription : white or off-white crystalline powder , odorless, tiny bitter . Easily soluble in methanol, soluble in alcohol, little soluble in water.
Quality Standard : EP
Application : Paroxetine is new antidepressant and indicated for the treatment of various major depressive disorder. The efficacy of paroxetine is to be linked to potentiation of serotonergic activity in the central nervous system resulting from competitive inhibition of neuronal presynapse membrane reuptake of 5- hydroxylamine and cause the accumulation of the latter in synaptic cleft, help the impulsion transmission of 5-hydroxylamine to nerve. The selective is higher than fluxetin, sertraline and clomipramine. Paroxetine is not sedative actions. Normal dosage has no affect on heart rate and blood pressure. Paroxetine has very low affinity for cholinergic, histamine or adrenergic receptors. Adverse event in anti-cholin and cardiovascular is lower than tricyclic antidepressant desipramine. It did not produce impairment of intellectual function or psychomotor performance. The acute and chronic treatment was unchanged specifically in parameter of haematology, biochemistry and urogenital.
Package : 5kg/tin .
Storage : sealed , keep in room temperature.
Period of retest : three years temporary.

Other Products

Product Name Cas No. Description
Product Name:
Panobinostat
Model:
404950-80-7
Description:
≥98%(HPLC)
Product Name:
pyraclostrobin
Model:
175013-18-0
Description:
Product Name:
Pentagastrin
Model:

Description:
C37H50N7O9S1
Product Name:
Pentoxyverine Citrate
Model:
23142-01-0
Description:
CP/NF
Product Name:
Protein Kinase C (530-558)
Model:
122613-29-0
Description:
C148H220N34O51S2
Product Name:
Pergolide Mesylate
Model:
66104-23-2
Description:
Product Name:
PLX4720
Model:
918505-84-7
Description:
≥98%(HPLC)
more