Iohexol
Item
Standards
Appearance
White to off-white hygroscopic, odorless powder
Identification
A: IR
B: UV
C: TLC
D: Masculine reaction
Specific rotation
-0.5°to +0.5°
Water
3.0%max
Heavy metals
0.001%max
Free aromatic amine
0.05%max
Free iodine
Meet the requirement
Free iodide
Ionic compounds
0.01%max
Methanol
50ppm max
Isopropyl alcohol
Methoxyethanol
20ppm max
n-Butanol
3-Chloro-1,2-propanedio
25ppm max
Related substances
O-alkylated compounds: 0.50%max
Any individual impurity: 0.10%max
All impurities: 0.30%max
Assay
98.5-102.0%