Name
Efavirenz
Synonyms
(4S)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one
Molecular Structure
Molecular Formula
C14H9ClF3NO2
Molecular Weight
315.675
CAS Registry Number
154598-52-4
Appearance
White to off-white powder
Solubility
Freely soluble in methanol an dichloromethane
Water
0.5%max
Specific optical rotation
-90.0°~ -100.0°
Related substance by HPLC
Maximum single unknown impurity: 0.10%max
Total impurities: 0.50%max
Chiral purity by HPLC
ENANTIOMER : 0.50%max
Assay by HPLC
98.0-102.0%