CHANGZHOU HIGHASSAY® CHEMICAL CO., LTD

Name

5-Azacytidine

Synonyms

4-Amino-1-beta-D-ribofuranosyl-1,3,5-triazine-2(1H)-one;Azacitidine

Molecular Structure

Molecular Formula

C₈H₁₂N₄O₅

Molecular Weight

244.21

CAS Registry Number

320-67-2

EINECS

206-280-2

Items

Standard

Appearance

A white to off white powder

Identification

IR

HPLC

PXRD

Appearance of solution

Clear and NMT B5 or BY5 or Y5

PH

6.0-8.5

Optical rotation

+37.0° to +41.0°

Heavy metals

20ppm max

Sulfate ash

0.1%max

Related substances

Monoacetyl-AZA: 0.15%max

Impurity UK1(RRT1.07): 0.10%max

Impurity UK2(RRT1.09): 0.10%max

Single unknown impurity: 0.10%max

Total impurities: 1.0%max

Residual solvents

Methanol: 0.15%max

DMSO: 0.15%max

2-propanol: 0.05%max

Dichloromethane: 0.01%max

Methyl formate: 0.02%max

Methyl acetate: 0.02%max

Purity

99.0%min

Assay by HPLC

98.0-102.0%

Bacterial Endotoxin

1.25EU/mg max